Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells, taken without her knowledge, became one of the most important tools in medicine. The first immortal human cells grown in culture, they are still alive today, though she has been dead for more than 60 years.

If you could pile all HeLa cells ever grown onto a scale, they'd weigh more than 50 million metric tons as much as a hundred Empire State Buildings.

HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bombs effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.

Now, Rebecca Skloot takes us on an extraordinary journey, from the colored ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henriettas small, dying hometown of Clover, Virginia, a land of wooden slave quarters, faith healings, and voodoo, to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.

Henrietta's family did not learn of her immortality until more than 20 years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimilliondollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family, past and present, is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.

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